Pesquisa sobre: ALKB ENZYMES 
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Descritor Inglês:   AlkB Enzymes 
Descritor Espanhol:   Enzimas AlkB 
Descritor Português:   Enzimas AlkB 
Sinônimos Inglês:   AlkB Homologs
Alkylated DNA Repair Protein AlkB Homologs
Alkylation Repair Homolog Proteins
Alkylation Repair Homologs
Enzymes, AlkB  
Categoria:   D08.811.074.062
D08.811.682.690.416.139
Definição Inglês:   A family of alpha- KETOGLUTARIC ACID and Fe(II)-dependent dioxygenases that are homologous to AlkB, an enzyme that repairs alkylated nucleic acids in E. coli. The mammalian homologs have diverse substrate specificities and functions that include DNA REPAIR, generating unique wobble modifications in URIDINE tRNA, demethylation of nucleotides in DNA and RNA, and demethylation of LYSINE residues on certain proteins, including ACTIN and histones (HISTONE CODE). 
Nota Histórica Inglês:   2017 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   56458 
Identificador Único:   D000071496 

Ocorrência na BVS:
 

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